NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase

BACKGROUND: HIV-1 integration results in genomic DNA gaps that are repaired by cellular DNA repair pathways. This step of the lentiviral life cycle remains poorly understood despite its crucial importance for successful replication. We and others reported that Ku70 protein of the non-homologous end...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Retrovirology
Prif Awduron: Knyazhanskaya, Ekaterina, Anisenko, Andrey, Shadrina, Olga, Kalinina, Anastasia, Zatsepin, Timofei, Zalevsky, Arthur, Mazurov, Dmitriy, Gottikh, Marina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833283/
https://ncbi.nlm.nih.gov/pubmed/31690330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-019-0492-z
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