NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase

BACKGROUND: HIV-1 integration results in genomic DNA gaps that are repaired by cellular DNA repair pathways. This step of the lentiviral life cycle remains poorly understood despite its crucial importance for successful replication. We and others reported that Ku70 protein of the non-homologous end...

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Vydáno v:Retrovirology
Hlavní autoři: Knyazhanskaya, Ekaterina, Anisenko, Andrey, Shadrina, Olga, Kalinina, Anastasia, Zatsepin, Timofei, Zalevsky, Arthur, Mazurov, Dmitriy, Gottikh, Marina
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833283/
https://ncbi.nlm.nih.gov/pubmed/31690330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-019-0492-z
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