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Increase of reactive oxygen species contributes to growth inhibition by fluconazole in Cryptococcus neoformans

BACKGROUND: Cryptococcus neoformans, a basidiomycetous yeast, is a fungal pathogen that can colonize the lungs of humans causing pneumonia and fungal meningitis in severely immunocompromised individuals. Recent studies have implied that the antifungal drug fluconazole (FLC) can induce oxidative stre...

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Dades bibliogràfiques
Publicat a:BMC Microbiol
Autors principals: Dbouk, Nadir Hani, Covington, Madison Bailey, Nguyen, Kenny, Chandrasekaran, Srikripa
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833255/
https://ncbi.nlm.nih.gov/pubmed/31694529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1606-4
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