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Investigation of the methylerythritol 4-phosphate pathway for microbial terpenoid production through metabolic control analysis

BACKGROUND: Terpenoids are of high interest as chemical building blocks and pharmaceuticals. In microbes, terpenoids can be synthesized via the methylerythritol phosphate (MEP) or mevalonate (MVA) pathways. Although the MEP pathway has a higher theoretical yield, metabolic engineering has met with l...

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Volke, Daniel Christoph, Rohwer, Johann, Fischer, Rainer, Jennewein, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833178/
https://ncbi.nlm.nih.gov/pubmed/31690314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1235-5
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