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Investigation of the methylerythritol 4-phosphate pathway for microbial terpenoid production through metabolic control analysis

BACKGROUND: Terpenoids are of high interest as chemical building blocks and pharmaceuticals. In microbes, terpenoids can be synthesized via the methylerythritol phosphate (MEP) or mevalonate (MVA) pathways. Although the MEP pathway has a higher theoretical yield, metabolic engineering has met with l...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Volke, Daniel Christoph, Rohwer, Johann, Fischer, Rainer, Jennewein, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833178/
https://ncbi.nlm.nih.gov/pubmed/31690314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1235-5
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