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Synthesis of Trichodermin Derivatives and Their Antimicrobial and Cytotoxic Activities

Trichothecene mycotoxins are recognized as highly bioactive compounds that can be used in the design of new useful bioactive molecules. In Trichoderma brevicompactum, the first specific step in trichothecene biosynthesis is carried out by a terpene cyclase, trichodiene synthase, that catalyzes the c...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Barúa, Javier E., de la Cruz, Mercedes, de Pedro, Nuria, Cautain, Bastien, Hermosa, Rosa, Cardoza, Rosa E., Gutiérrez, Santiago, Monte, Enrique, Vicente, Francisca, Collado, Isidro G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833013/
https://ncbi.nlm.nih.gov/pubmed/31652666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24203811
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