Classical Hodgkin’s Lymphoma in the Era of Immune Checkpoint Inhibition

The ligation of programmed cell death 1 (PD-1) with programmed cell death ligand PD-L activates the immune checkpoint leading to T-cell dysfunction, exhaustion, and tolerance, especially in Hodgkin lymphoma (HL) where the PD-L/ Janus kinase (Jak) signaling was frequently found altered. Anti-PD-1 or...

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Bibliographic Details
Published in:J Clin Med
Main Authors: De Re, Valli, Caggiari, Laura, Repetto, Ombretta, Mussolin, Lara, Mascarin, Maurizio
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832444/
https://ncbi.nlm.nih.gov/pubmed/31581738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8101596
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