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Classical Hodgkin’s Lymphoma in the Era of Immune Checkpoint Inhibition
The ligation of programmed cell death 1 (PD-1) with programmed cell death ligand PD-L activates the immune checkpoint leading to T-cell dysfunction, exhaustion, and tolerance, especially in Hodgkin lymphoma (HL) where the PD-L/ Janus kinase (Jak) signaling was frequently found altered. Anti-PD-1 or...
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| Pubblicato in: | J Clin Med |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6832444/ https://ncbi.nlm.nih.gov/pubmed/31581738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8101596 |
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