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Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells

Clostridium perfringens enterotoxin (CPE) contributes to diarrhea and an often-lethal enterotoxemia. CPE action starts when it binds to claudin receptors, forming a small complex (90 kDa). Six small complexes then oligomerize to create prepores, followed by insertion of beta-hairpins from CPE to for...

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Bibliographic Details
Published in:Toxins (Basel)
Main Authors: Mehdizadeh Gohari, Iman, Li, Jihong, Navarro, Mauricio, Uzal, Francisco, McClane, Bruce
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832201/
https://ncbi.nlm.nih.gov/pubmed/31601044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11100582
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