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Chlojaponilactone B Attenuates Lipopolysaccharide-Induced Inflammatory Responses by Suppressing TLR4-Mediated ROS Generation and NF-κB Signaling Pathway

The lindenane-type sesquiterpenoid chlojaponilactone B (1), isolated from Chloranthus japonicus, has been reported to possess anti-inflammatory properties. The present study aimed to further explore the molecular mechanisms underlying the anti-inflammatory activity of 1. RNA-seq analyses revealed th...

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Ye, Shaoxia, Zheng, Qiyao, Zhou, Yang, Bai, Bai, Yang, Depo, Zhao, Zhimin
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832138/
https://ncbi.nlm.nih.gov/pubmed/31623197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24203731
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