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Quantitative Proteome Analysis of Atg5-Deficient Mouse Embryonic Fibroblasts Reveals the Range of the Autophagy-Modulated Basal Cellular Proteome

Basal autophagy is crucial for maintenance of cellular homeostasis. ATG5 is an essential protein for autophagosome formation, and its depletion has been extensively used as a tool to disrupt autophagy. Here, we characterize the impact of Atg5 deficiency on the cellular proteome of mouse embryonic fi...

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Pubblicato in:mSystems
Autori principali: Sharma, Kiran Bala, Sharma, Manish, Aggarwal, Suruchi, Yadav, Amit Kumar, Bhatnagar, Shinjini, Vrati, Sudhanshu, Kalia, Manjula
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832020/
https://ncbi.nlm.nih.gov/pubmed/31690592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00481-19
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