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Metformin induces lipid changes on sphingolipid species and oxidized lipids in polycystic ovary syndrome women

Metformin is one of the treatments used for PCOS pathology decreasing body weight, plasma androgen, FSH and glucose levels. Unfortunately, there is little known about metformin’s effects on lipid metabolism, a crucial process in PCOS pathology. We have employed a lipidomic approach to explore altera...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Pradas, Irene, Rovira-Llopis, Susana, Naudí, Alba, Bañuls, Celia, Rocha, Milagros, Hernandez-Mijares, Antonio, Pamplona, Reinald, Victor, Victor M., Jové, Mariona
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831788/
https://ncbi.nlm.nih.gov/pubmed/31690730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52263-w
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