Single-cell RNA-sequencing analysis of estrogen- and endocrine-disrupting chemical-induced reorganization of mouse mammary gland

Menopause is a critical window of susceptibility for its sensitivity to endocrine disrupting chemicals due to the decline of endogenous estrogen. Using a surgical menopausal (ovariectomized) mouse model, we assessed how mammary tissue was affected by both 17β-estradiol (E2) and polybrominated diphen...

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Publicado en:Commun Biol
Main Authors: Kanaya, Noriko, Chang, Gregory, Wu, Xiwei, Saeki, Kohei, Bernal, Lauren, Shim, Hyun-Jeong, Wang, Jinhui, Warden, Charles, Yamamoto, Takuro, Li, Jay, Park, June-Soo, Synold, Timothy, Vonderfecht, Steve, Rakoff, Michele, Neuhausen, Susan L., Chen, Shiuan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831695/
https://ncbi.nlm.nih.gov/pubmed/31701034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0618-9
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