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Prevention of calpain-dependent degradation of STK38 by MEKK2-mediated phosphorylation

Serine-threonine kinase 38 (STK38) is a member of the protein kinase A (PKA)/PKG/PKC-family implicated in the regulation of cell division and morphogenesis. However, the molecular mechanisms underlying STK38 stability remain largely unknown. Here, we show that treatment of cells with either heat or...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Enomoto, Atsushi, Fukasawa, Takemichi, Tsumoto, Hiroki, Karube, Masataka, Nakagawa, Keiichi, Yoshizaki, Ayumi, Sato, Shinichi, Miura, Yuri, Miyagawa, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831656/
https://ncbi.nlm.nih.gov/pubmed/31690749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52435-8
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