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The second and third amino acids of Pam2 lipopeptides are key for the proliferation of cytotoxic T cells

The TLR2 agonist, dipalmitoyl lipopeptide (Pam2LP), has been used as an immune adjuvant without much success. Pam2LP is recognised by TLR2/6 receptors in humans and in mice. This study examined the proliferative activity of cytotoxic T lymphocytes (CTL) using mouse Ag-presenting dendritic cells (DCs...

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Bibliografische gegevens
Gepubliceerd in:Innate Immun
Hoofdauteurs: Takeda, Yohei, Azuma, Masahiro, Hatsugai, Ryoko, Fujimoto, Yukari, Hashimoto, Masahito, Fukase, Koichi, Matsumoto, Misako, Seya, Tsukasa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830919/
https://ncbi.nlm.nih.gov/pubmed/29848176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425918777598
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