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Lipoxin A(4) attenuates LPS-induced acute lung injury via activation of the ACE2-Ang-(1-7)-Mas axis

Previous studies have reported that lipoxin A4 (LXA4) and the angiotensin I-converting enzyme 2 (ACE2), angiotensin-(1-7) [Ang-(1-7)], and its receptor Mas [ACE2-Ang-(1-7)-Mas] axis play important protective roles in acute lung injury (ALI). However, there is still no direct evidence of LXA4-mediate...

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Bibliografiske detaljer
Udgivet i:Innate Immun
Main Authors: Chen, Qiong-Feng, Kuang, Xiao-Dong, Yuan, Qi-Feng, Hao, Hua, Zhang, Ting, Huang, Yong-Hong, Zhou, Xiao-Yan
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830918/
https://ncbi.nlm.nih.gov/pubmed/29969931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425918785008
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