Diagnostic biomarkers for adult haemophagocytic lymphohistiocytosis in critically ill patients (HEMICU): a prospective observational study protocol

INTRODUCTION: Haemophagocytic lymphohistiocytosis (HLH) in adults is characterised by toxic immune activation and a sepsis-like syndrome, leading to high numbers of undiagnosed cases and mortality rates of up to 68%. Early diagnosis and specific immune suppressive treatment are mandatory to avoid fa...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Lachmann, Gunnar, Knaak, Cornelia, von Haefen, Clarissa, Paeschke, Nadine, Meisel, Christian, Nyvlt, Peter, Schuster, Friederike S, Piper, Sophie K, Kruppa, Jochen, Vorderwülbecke, Gerald, Balzer, Felix, La Rosée, Paul, Schenk, Thomas, Unterwalder, Nadine, Kölsch, Uwe, Lachmann, Nils, Akyüz, Levent, Brunkhorst, Frank M, Volk, Hans-Dieter, Keh, Didier, Spies, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Intensive Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830715/
https://ncbi.nlm.nih.gov/pubmed/31666276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-032695
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