Ketamine Increases Proliferation of Human iPSC-Derived Neuronal Progenitor Cells via Insulin-Like Growth Factor 2 and Independent of the NMDA Receptor

The N-methyl-D-aspartate (NMDA) receptor antagonist ketamine offers promising perspectives for the treatment of major depressive disorder. Although ketamine demonstrates rapid and long-lasting effects, even in treatment-resistant patients, to date, the underlying mode of action remains elusive. Thus...

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Foilsithe in:Cells
Main Authors: Grossert, Alessandra, Mehrjardi, Narges Zare, Bailey, Sarah J., Lindsay, Mark A., Hescheler, Jürgen, Šarić, Tomo, Teusch, Nicole
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830315/
https://ncbi.nlm.nih.gov/pubmed/31554266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101139
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