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A comparative study of single-particle cryo-EM with liquid-nitrogen and liquid-helium cooling

Radiation damage is the most fundamental limitation for achieving high resolution in electron cryo-microscopy (cryo-EM) of biological samples. The effects of radiation damage are reduced by liquid-helium cooling, although the use of liquid helium is more challenging than that of liquid nitrogen. To...

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Detalhes bibliográficos
Publicado no:IUCrJ
Main Authors: Pfeil-Gardiner, Olivia, Mills, Deryck J., Vonck, Janet, Kuehlbrandt, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830223/
https://ncbi.nlm.nih.gov/pubmed/31709065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252519011503
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