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Mutagenesis facilitated crystallization of GLP-1R
The class B family of G-protein-coupled receptors (GPCRs) has long been a paradigm for peptide hormone recognition and signal transduction. One class B GPCR, the glucagon-like peptide-1 receptor (GLP-1R), has been considered as an anti-diabetes drug target and there are several peptidic drugs availa...
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| Publié dans: | IUCrJ |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
International Union of Crystallography
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6830218/ https://ncbi.nlm.nih.gov/pubmed/31709055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252519013496 |
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