Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology

Background: Retroelements (REs) are mobile genetic elements comprising ~40% of human DNA. They can reshape expression patterns of nearby genes by providing various regulatory sequences. The proportion of regulatory sequences held by REs can serve a measure of regulatory evolution rate of the respect...

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Pubblicato in:Cells
Autori principali: Nikitin, Daniil, Kolosov, Nikita, Murzina, Anastasiia, Pats, Karina, Zamyatin, Anton, Tkachev, Victor, Sorokin, Maxim, Kopylov, Philippe, Buzdin, Anton
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830109/
https://ncbi.nlm.nih.gov/pubmed/31597351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101219
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