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An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK-STAT signaling components

BACKGROUND: Since its discovery almost three decades ago, the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway has paved the road for understanding inflammatory and immunity processes related to a wide range of human pathologies including cancer. Several studies hav...

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Vydáno v:Mol Med
Hlavní autoři: Chang, Wai Hoong, Lai, Alvina G.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829980/
https://ncbi.nlm.nih.gov/pubmed/31684858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-019-0114-1
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