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Below the Surface: IGF-1R Therapeutic Targeting and Its Endocytic Journey
Ligand-activated plasma membrane receptors follow pathways of endocytosis through the endosomal sorting apparatus. Receptors cluster in clathrin-coated pits that bud inwards and enter the cell as clathrin-coated vesicles. These vesicles travel through the acidic endosome whereby receptors and ligand...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829878/ https://ncbi.nlm.nih.gov/pubmed/31600876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101223 |
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