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SGK regulates pH increase and cyclin B–Cdk1 activation to resume meiosis in starfish ovarian oocytes

Tight regulation of intracellular pH (pH(i)) is essential for biological processes. Fully grown oocytes, having a large nucleus called the germinal vesicle, arrest at meiotic prophase I. Upon hormonal stimulus, oocytes resume meiosis to become fertilizable. At this time, the pH(i) increases via Na(+...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Hosoda, Enako, Hiraoka, Daisaku, Hirohashi, Noritaka, Omi, Saki, Kishimoto, Takeo, Chiba, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829648/
https://ncbi.nlm.nih.gov/pubmed/31537709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201812133
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