Receptor Heterodimerization and Co-Receptor Engagement in TLR2 Activation Induced by MIC1 and MIC4 from Toxoplasma gondii

The microneme organelles of Toxoplasma gondii tachyzoites release protein complexes (MICs), including one composed of the transmembrane protein MIC6 plus MIC1 and MIC4. In this complex, carbohydrate recognition domains of MIC1 and MIC4 are exposed and interact with terminal sialic acid and galactose...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Costa Mendonça-Natividade, Flávia, Duque Lopes, Carla, Ricci-Azevedo, Rafael, Sardinha-Silva, Aline, Figueiredo Pinzan, Camila, Paiva Alegre-Maller, Ana Claudia, L. Nohara, Lilian, B. Carneiro, Alan, Panunto-Castelo, Ademilson, C. Almeida, Igor, Roque-Barreira, Maria Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829480/
https://ncbi.nlm.nih.gov/pubmed/31658592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205001
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