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Fast Screening of Inhibitor Binding/Unbinding Using Novel Software Tool CaverDock

Protein tunnels and channels are attractive targets for drug design. Drug molecules that block the access of substrates or release of products can be efficient modulators of biological activity. Here, we demonstrate the applicability of a newly developed software tool CaverDock for screening databas...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Pinto, Gaspar P., Vavra, Ondrej, Filipovic, Jiri, Stourac, Jan, Bednar, David, Damborsky, Jiri
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828983/
https://ncbi.nlm.nih.gov/pubmed/31737596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00709
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