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Pancreatic cancer-educated macrophages protect cancer cells from complement-dependent cytotoxicity by up-regulation of CD59

Tumor-associated macrophages (TAMs) are versatile immune cells that promote a variety of malignant behaviors of pancreatic cancer. CD59 is a GPI-anchored membrane protein that prevents complement activation by inhibiting the formation of the membrane attack complex, which may protect cancer cells fr...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Ronghua, Liu, Qiaofei, Peng, Junya, Wang, Mengyi, Gao, Xiang, Liao, Quan, Zhao, Yupei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828776/
https://ncbi.nlm.nih.gov/pubmed/31685825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2065-4
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