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Decreased integrity of exercise-induced plasma cell free nuclear DNA – negative association with the increased oxidants production by circulating phagocytes

Strenuous exercise increases circulating cell free DNA (cfDNA) and stimulates blood phagocytes to generate reactive oxygen species (ROS) which may induce DNA strand breaks. We tested whether: (A) elevated cfDNA in response to three repeated bouts of exhaustive exercise has decreased integrity; (B) e...

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Vydáno v:Sci Rep
Hlavní autoři: Stawski, Robert, Walczak, Konrad, Perdas, Ewelina, Wlodarczyk, Anna, Sarniak, Agata, Kosielski, Piotr, Meissner, Pawel, Budlewski, Tomasz, Padula, Gianluca, Nowak, Dariusz
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828751/
https://ncbi.nlm.nih.gov/pubmed/31685910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52409-w
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