Translating Systems Medicine Into Clinical Practice: Examples From Pulmonary Medicine With Genetic Disorders, Infections, Inflammations, Cancer Genesis, and Treatment Implication of Molecular Alterations in Non-small-cell Lung Cancers and Personalized Medicine

Non-small-cell lung cancers (NSCLC) represent 85% of all lung cancers, with adenocarcinoma as the most common subtype. Since the 2000's, the discovery of molecular alterations including epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements togethe...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Pinsolle, Julian, McLeer-Florin, Anne, Giaj Levra, Matteo, de Fraipont, Florence, Emprou, Camille, Gobbini, Elisa, Toffart, Anne-Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828737/
https://ncbi.nlm.nih.gov/pubmed/31737634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2019.00233
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