Cerebrospinal Fluid Drug Concentrations and Clinical Outcome of Patients with Neoplastic Meningitis Treated with Liposomal Cytarabine

BACKGROUND AND OBJECTIVE: Liposomal cytarabine is a slow-release formulation for intrathecal application in patients with neoplastic meningitis. Although standard dosing intervals range from 2 to 4 weeks, it is unclear whether sustained cytotoxic cerebrospinal fluid (CSF) concentrations can be achie...

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書目詳細資料
發表在:Eur J Drug Metab Pharmacokinet
Main Authors: Bohn, Jan-Paul, Reinstadler, Vera, Pall, Georg, Stockhammer, Günther, Steurer, Michael, Oberacher, Herbert, Wolf, Dominik
格式: Artigo
語言:Inglês
出版: Springer International Publishing 2019
主題:
Short Communication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828631/
https://ncbi.nlm.nih.gov/pubmed/31435852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-019-00572-w
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