A Type 1 Diabetes Genetic Risk Score can identify patients with GAD65 autoantibody positive type 2 diabetes that rapidly progress to insulin therapy

OBJECTIVE: Progression to insulin therapy in clinically diagnosed type 2 diabetes is highly variable. GAD65 autoantibodies (GADA) are associated with faster progression, but their predictive value is limited. We aimed to determine if a Type 1 Diabetes Genetic Risk Score (T1DGRS) could predict rapid...

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Detalhes bibliográficos
Publicado no:Diabetes Care
Main Authors: Grubb, Anita L, McDonald, Timothy J, Rutters, Femke, Donnelly, Louise A, Hattersley, Andrew T, Oram, Richard A, Palmer, Colin NA, van der Heijden, Amber A, Carr, Fiona, Elders, Petra J M, Weedon, Mike N, Slieker, Roderick C, Hart, Leen M 't, Pearson, Ewan R, Shields, Beverley M, Jones, Angus G
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828553/
https://ncbi.nlm.nih.gov/pubmed/30352895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc18-0431
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