Genomic Subtyping and Therapeutic Targeting of Acute Erythroleukemia

Acute erythroid leukemia (AEL) is a high risk leukemia of poorly understood genetic basis, with controversy regarding diagnosis in the spectrum of myelodysplasia and myeloid leukemia. We compared genomic features of 159 childhood and adult AEL cases to non-AEL myeloid disorders, and defined 5 age-re...

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Publicat a:Nat Genet
Autors principals: Iacobucci, Ilaria, Wen, Ji, Meggendorfer, Manja, Choi, John K., Shi, Lei, Pounds, Stanley B., Carmichael, Catherine L., Masih, Katherine E., Morris, Sarah M., Lindsley, R. Coleman, Janke, Laura J., Alexander, Thomas B., Song, Guangchun, Qu, Chunxu, Li, Yongjin, Payne-Turner, Debbie, Tomizawa, Daisuke, Kiyokawa, Nobutaka, Valentine, Marcus, Valentine, Virginia, Basso, Giuseppe, Locatelli, Franco, Enemark, Eric J., Kham, Shirley K. Y., Yeoh, Allen E. J., Ma, Xiaotu, Zhou, Xin, Sioson, Edgar, Rusch, Michael, Ries, Rhonda E., Stieglitz, Elliot, Hunger, Stephen P., Wei, Andrew H., To, L Bik, Lewis, Ian D., D’Andrea, Richard J., Kile, Benjamin T., Brown, Anna L., Scott, Hamish S., Hahn, Christopher N., Marlton, Paula, Pei, Deqing, Cheng, Cheng, Loh, Mignon L., Ebert, Benjamin L., Meshinchi, Soheil, Haferlach, Torsten, Mullighan, Charles G.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828160/
https://ncbi.nlm.nih.gov/pubmed/30926971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0375-1
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