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Mutations of the Bacillus subtilis YidC1 (SpoIIIJ) insertase alleviate stress associated with σ(M)-dependent membrane protein overproduction
In Bacillus subtilis, the extracytoplasmic function σ factor σ(M) regulates cell wall synthesis and is critical for intrinsic resistance to cell wall targeting antibiotics. The anti-σ factors YhdL and YhdK form a complex that restricts the basal activity of σ(M), and the absence of YhdL leads to run...
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| 發表在: | PLoS Genet |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6827917/ https://ncbi.nlm.nih.gov/pubmed/31626625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008263 |
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