Proteomic Profiling of Mouse Brains Exposed to Blast-Induced Mild Traumatic Brain Injury Reveals Changes in Axonal Proteins and Phosphorylated Tau

Alzheimer’s disease (AD), the most prevalent form of dementia, is characterized by two pathological hallmarks: Tau-containing neurofibrillary tangles and amyloid-β protein (Aβ)-containing neuritic plaques. The goal of this study is to understand mild traumatic brain injury (mTBI)-related brain prote...

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Veröffentlicht in:J Alzheimers Dis
Hauptverfasser: Chen, Mei, Song, Hailong, Cui, Jiankun, Johnson, Catherine E., Hubler, Graham K., DePalma, Ralph G., Gu, Zezong, Xia, Weiming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827339/
https://ncbi.nlm.nih.gov/pubmed/30347620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180726
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