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COOLAIR antisense RNAs form evolutionarily conserved elaborate secondary structures

There is considerable debate about the functionality of long non-coding RNAs (lncRNAs). Lack of sequence conservation has been used to argue against functional relevance. We investigate antisense lncRNAs called COOLAIR at the A. thaliana FLC locus and have experimentally determined their secondary s...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Hawkes, Emily J., Hennelly, Scott P., Novikova, Irina V., Irwin, Judith A., Dean, Caroline, Sanbonmatsu, Karissa Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827332/
https://ncbi.nlm.nih.gov/pubmed/27653675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.045
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