Xanthoxyletin Inhibits Proliferation of Human Oral Squamous Carcinoma Cells and Induces Apoptosis, Autophagy, and Cell Cycle Arrest by Modulation of the MEK/ERK Signaling Pathway

BACKGROUND: This study aimed to investigate the effects of xanthoxyletin, a plant-derived coumarin, on human oral squamous cancer cells in vitro and in mouse xenografts in vivo. MATERIA/METHODS: The study included SCC-1 human oral cancer cells and EBTr normal embryonic bovine tracheal epithelial cel...

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Vydáno v:Med Sci Monit
Hlavní autoři: Wen, Qingquan, Luo, Kai, Huang, Haiyan, Liao, Weiguo, Yang, Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2019
Témata:
Lab/In Vitro Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827329/
https://ncbi.nlm.nih.gov/pubmed/31654522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.911697
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