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Human cardiac myosin–binding protein C restricts actin structural dynamics in a cooperative and phosphorylation-sensitive manner

Cardiac myosin–binding protein C (cMyBP-C) is a thick filament-associated protein that influences actin-myosin interactions. cMyBP-C alters myofilament structure and contractile properties in a protein kinase A (PKA) phosphorylation-dependent manner. To determine the effects of cMyBP-C and its phosp...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Bunch, Thomas A., Kanassatega, Rhye-Samuel, Lepak, Victoria C., Colson, Brett A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827302/
https://ncbi.nlm.nih.gov/pubmed/31519753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009543
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