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Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells

Epidemiologic studies link organophosphorus pesticides (OPs) to increased incidence of asthma. In guinea pigs, OP-induced airway hyperreactivity requires macrophages and TNF-α. Here, we determined whether OPs interact directly with macrophages to alter cytokine expression or release. Human THP1 cell...

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Foilsithe in:Am J Respir Cell Mol Biol
Main Authors: Proskocil, Becky J., Grodzki, Ana Cristina G., Jacoby, David B., Lein, Pamela J., Fryer, Allison D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Thoracic Society 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827067/
https://ncbi.nlm.nih.gov/pubmed/30978295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0257OC
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