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Effects of Lidocaine and Src Inhibition on Metastasis in a Murine Model of Breast Cancer Surgery
Breast cancer recurs in 20% of patients following intended curative resection. In vitro data indicates that amide local anaesthetics, including lidocaine, inhibit cancer cell metastasis by inhibiting the tyrosine kinase enzyme Src. In a murine breast cancer surgery model, systemic lidocaine reduces...
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| Udgivet i: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6826872/ https://ncbi.nlm.nih.gov/pubmed/31546727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101414 |
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