The Epithelial to Mesenchymal Transition Promotes Glutamine Independence by Suppressing GLS2 Expression

Identifying bioenergetics that facilitate the epithelial to mesenchymal transition (EMT) in breast cancer cells may uncover targets to treat incurable metastatic disease. Metastasis is the number one cause of cancer-related deaths; therefore, it is urgent to identify new treatment strategies to prev...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Ramirez-Peña, Esmeralda, Arnold, James, Shivakumar, Vinita, Joseph, Robiya, Vidhya Vijay, Geraldine, den Hollander, Petra, Bhangre, Neeraja, Allegakoen, Paul, Prasad, Rishika, Conley, Zachary, Matés, José M., Márquez, Javier, Chang, Jeffrey T., Vasaikar, Suhas, Soundararajan, Rama, Sreekumar, Arun, Mani, Sendurai A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826439/
https://ncbi.nlm.nih.gov/pubmed/31652551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101610
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