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Trefoil factor 2 activation of CXCR4 requires calcium mobilization to drive epithelial repair in gastric organoids

KEY POINTS: Determining the signalling cascade of epithelial repair, using murine gastric organoids, allows definition of regulatory processes intrinsic to epithelial cells, at the same time as validating and dissecting the signalling cascade with more precision than is possible in vivo. Following s...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Engevik, Kristen A., Hanyu, Hikaru, Matthis, Andrea L., Zhang, Tongli, Frey, Mark R., Oshima, Yusuke, Aihara, Eitaro, Montrose, Marshall H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826237/
https://ncbi.nlm.nih.gov/pubmed/30912855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277259
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