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Trefoil factor 2 activation of CXCR4 requires calcium mobilization to drive epithelial repair in gastric organoids

KEY POINTS: Determining the signalling cascade of epithelial repair, using murine gastric organoids, allows definition of regulatory processes intrinsic to epithelial cells, at the same time as validating and dissecting the signalling cascade with more precision than is possible in vivo. Following s...

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Bibliografski detalji
Izdano u:J Physiol
Glavni autori: Engevik, Kristen A., Hanyu, Hikaru, Matthis, Andrea L., Zhang, Tongli, Frey, Mark R., Oshima, Yusuke, Aihara, Eitaro, Montrose, Marshall H.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826237/
https://ncbi.nlm.nih.gov/pubmed/30912855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277259
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