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Notch and EGFR regulate apoptosis in progenitor cells to ensure gut homeostasis in Drosophila

The regenerative activity of adult stem cells carries a risk of cancer, particularly in highly renewable tissues. Members of the family of inhibitor of apoptosis proteins (IAPs) inhibit caspases and cell death, and are often deregulated in adult cancers; however, their roles in normal adult tissue h...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Reiff, Tobias, Antonello, Zeus A, Ballesta‐Illán, Esther, Mira, Laura, Sala, Salvador, Navarro, Maria, Martinez, Luis M, Dominguez, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826210/
https://ncbi.nlm.nih.gov/pubmed/31566767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101346
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