Spherical spindle shape promotes perpendicular cortical orientation by preventing isometric cortical pulling on both spindle poles during C. elegans female meiosis

Meiotic spindles are positioned perpendicular to the oocyte cortex to facilitate segregation of chromosomes into a large egg and a tiny polar body. In C. elegans, spindles are initially ellipsoid and parallel to the cortex before shortening to a near-spherical shape with flattened poles and then rot...

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Vydáno v:Development
Hlavní autoři: Vargas, Elizabeth, McNally, Karen P., Cortes, Daniel B., Panzica, Michelle T., Danlasky, Brennan M., Li, Qianyan, Maddox, Amy Shaub, McNally, Francis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826043/
https://ncbi.nlm.nih.gov/pubmed/31575646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.178863
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