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CRISPR/Cas9-mediated genome editing in nonhuman primates

Owing to their high similarity to humans, non-human primates (NHPs) provide an exceedingly suitable model for the study of human disease. In this Review, we summarize the history of transgenic NHP models and the progress of CRISPR/Cas9-mediated genome editing in NHPs, from the first proof-of-princip...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Dis Model Mech
Hauptverfasser: Kang, Yu, Chu, Chu, Wang, Fang, Niu, Yuyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826017/
https://ncbi.nlm.nih.gov/pubmed/31636095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.039982
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