Exosomes derived from statin-modified bone marrow dendritic cells increase thymus-derived natural regulatory T cells in experimental autoimmune myasthenia gravis

BACKGROUND: The thymus plays an essential role in the pathogenesis of myasthenia gravis (MG). In patients with MG, natural regulatory T cells (nTreg), a subpopulation of T cells that maintain tolerance to self-antigens, are severely impaired in the thymuses. In our previous study, upregulated nTreg...

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Bibliografiska uppgifter
I publikationen:J Neuroinflammation
Huvudupphovsmän: Zhang, Peng, Liu, Ru-Tao, Du, Tong, Yang, Chun-Lin, Liu, Yu-Dong, Ge, Meng-Ru, Zhang, Min, Li, Xiao-Li, Li, Heng, Dou, Ying-Chun, Duan, Rui-Sheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825716/
https://ncbi.nlm.nih.gov/pubmed/31679515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1587-0
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