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Wnt activator FOXB2 drives the neuroendocrine differentiation of prostate cancer

The Wnt signaling pathway is of paramount importance for development and disease. However, the tissue-specific regulation of Wnt pathway activity remains incompletely understood. Here we identify FOXB2, an uncharacterized forkhead box family transcription factor, as a potent activator of Wnt signali...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Moparthi, Lavanya, Pizzolato, Giulia, Koch, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825314/
https://ncbi.nlm.nih.gov/pubmed/31611391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906484116
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