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Alternative pathway androgen biosynthesis and human fetal female virilization

Androgen biosynthesis in the human fetus proceeds through the adrenal sex steroid precursor dehydroepiandrosterone, which is converted to testosterone in the gonads, followed by further activation to 5α-dihydrotestosterone in genital skin, thereby facilitating male external genital differentiation....

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Reisch, Nicole, Taylor, Angela E., Nogueira, Edson F., Asby, Daniel J., Dhir, Vivek, Berry, Andrew, Krone, Nils, Auchus, Richard J., Shackleton, Cedric H. L., Hanley, Neil A., Arlt, Wiebke
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825302/
https://ncbi.nlm.nih.gov/pubmed/31611378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906623116
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