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Cellular defects resulting from disease-related myosin II mutations in Drosophila

The nonmuscle myosin II motor protein produces forces that are essential to driving the cell movements and cell shape changes that generate tissue structure. Mutations in myosin II that are associated with human diseases are predicted to disrupt critical aspects of myosin function, but the mechanism...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kasza, Karen E., Supriyatno, Sara, Zallen, Jennifer A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825282/
https://ncbi.nlm.nih.gov/pubmed/31615886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909227116
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