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Cellular defects resulting from disease-related myosin II mutations in Drosophila

The nonmuscle myosin II motor protein produces forces that are essential to driving the cell movements and cell shape changes that generate tissue structure. Mutations in myosin II that are associated with human diseases are predicted to disrupt critical aspects of myosin function, but the mechanism...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kasza, Karen E., Supriyatno, Sara, Zallen, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825282/
https://ncbi.nlm.nih.gov/pubmed/31615886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909227116
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