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Alternatively spliced isoforms reveal a novel type of PTB domain in CCM2 protein

Cerebral cavernous malformations (CCMs) is a microvascular disorder in the central nervous system. Despite tremendous efforts, the causal genetic mutation in some CCM patients has not be identified, raising the possibility of an unknown CCM locus. The CCM2/MGC4607 gene has been identified as one of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Jiang, Xiaoting, Padarti, Akhil, Qu, Yanchun, Sheng, Shen, Abou-Fadel, Johnathan, Badr, Ahmed, Zhang, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825194/
https://ncbi.nlm.nih.gov/pubmed/31676827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52386-0
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