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Evidence that fodipir (DPDP) binds neurotoxic Pt(2+) with a high affinity: An electron paramagnetic resonance study

Oxaliplatin typically causes acute neuropathic problems, which may, in a dose-dependent manner, develop into a chronic form of chemotherapy-induced peripheral neuropathy (CIPN), which is associated with retention of Pt(2+) in the dorsal root ganglion. A clinical study by Coriat and co-workers sugges...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Stehr, Jan Eric, Lundström, Ingemar, Karlsson, Jan Olof G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825159/
https://ncbi.nlm.nih.gov/pubmed/31676855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52248-9
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