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Pain Inhibits GRPR Neurons via GABAergic Signaling in the Spinal Cord

It has been known that algogens and cooling could inhibit itch sensation; however, the underlying molecular and neural mechanisms remain poorly understood. Here, we show that the spinal neurons expressing gastrin releasing peptide receptor (GRPR) primarily comprise excitatory interneurons that recei...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bardoni, Rita, Shen, Kai-Feng, Li, Hui, Jeffry, Joseph, Barry, Devin M., Comitato, Antonella, Li, Yun-Qing, Chen, Zhou-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825123/
https://ncbi.nlm.nih.gov/pubmed/31676846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52316-0
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