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Inhibition of γ/β Globin Gene Switching in CD 34(+) Derived Erythroid Cells by BCL11A RNA Silencing
The induction of fetal haemoglobin (Hb F), due to the sustained clinical effects, is one of the most promising methods for the treatment of β hemoglobinopathies, such as thalassemia major and sickle cell disease (SCD). Inhibition of γ-globin gene silencing, possibly is a suitable strategy to induce...
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| Publicado no: | Indian J Hematol Blood Transfus |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer India
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6825069/ https://ncbi.nlm.nih.gov/pubmed/31741633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12288-019-01131-8 |
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