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Inhibition of γ/β Globin Gene Switching in CD 34(+) Derived Erythroid Cells by BCL11A RNA Silencing

The induction of fetal haemoglobin (Hb F), due to the sustained clinical effects, is one of the most promising methods for the treatment of β hemoglobinopathies, such as thalassemia major and sickle cell disease (SCD). Inhibition of γ-globin gene silencing, possibly is a suitable strategy to induce...

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Bibliografski detalji
Izdano u:Indian J Hematol Blood Transfus
Glavni autori: Taghavi, Seyyed Asadallah, Hosseini, Kamran Mousavi, Tamaddon, Gholamhossein, Kasraian, Leila
Format: Artigo
Jezik:Inglês
Izdano: Springer India 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825069/
https://ncbi.nlm.nih.gov/pubmed/31741633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12288-019-01131-8
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