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Central nervous system-specific efficacy of CDK4/6 inhibitors in randomized controlled trials for metastatic breast cancer

Importance: Metastatic breast cancer with central nervous system (CNS) metastases carries a poor prognosis. Recently, CDK4/6 inhibitors have demonstrated a progression free survival (PFS) and overall survival benefit when combined with standard endocrine therapy in advanced hormone receptor (HR)+/HE...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Nguyen, Long V., Searle, Karlee, Jerzak, Katarzyna J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824870/
https://ncbi.nlm.nih.gov/pubmed/31695840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27238
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